McDonald's said it was temporarily closing its roughly 850 restaurants in Russia, while Starbucks also said its 100 coffee shops would shut.On Wednesday, Heineken stopped beer production and sales in Russia.
And Mothercare said all business in Russia, which represents 20% to 25% of its global sales, had been stopped.
Elsewhere, tobacco company Imperial Brands - the group behind brands including JPS and Davidoff cigarettes - said it was pausing production at its factory in Volgograd in a move impacting about 1,000 employees. It has already suspended its operations in Ukraine over staff safety concerns.
The moves by McDonald's, Coca-Cola and Starbucks come after mounting pressure on companies to act over the war in Ukraine. All three firms said they would continue to pay their staff.
Companies have been under pressure to act as Russian violence against civilians has escalated.
#BoycottMcDonalds and #BoycottCocaCola had both been trending on Twitter over recent days.